Metabolic reprogramming by KSHV in cellular transformation
نویسندگان
چکیده
منابع مشابه
Metabolic reprogramming by KSHV in cellular transformation
Oncogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally linked to several human cancers including Kaposi’s sarcoma and primary effusion lymphoma. Despite intensive studies, little is known about how KSHV alters cellular metabolism during cellular transformation. Using a novel model of KSHV-induced cellular transformation of primary rat embryonic metanephric mesenchymal stem cells (...
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Infections by viruses are associated with approximately 12% of human cancer. Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several malignancies commonly found in AIDS patients. The mechanism of KSHV-induced oncogenesis remains elusive, due in part to the lack of an adequate experimental system for cellular transformation of primary cells. Here, we report efficient infecti...
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ژورنال
عنوان ژورنال: Cancer & Metabolism
سال: 2014
ISSN: 2049-3002
DOI: 10.1186/2049-3002-2-s1-p88